Read e-book online Age-Related Macular Degeneration PDF

By D. Virgil Alfaro III et al.

ISBN-10: 1451151691

ISBN-13: 9781451151695

Stay brand new with the newest advancements on your box with the highly-anticipated moment variation of Age-Related Macular Degeneration. This accomplished textual content covers fresh advances in pathophysiology, analysis, and therapy together with promising new advancements that would have an effect on your sufferer care. Dr. Virgil Alfaro and his colleagues at Retina experts of Charleston carry you their services within the parts of uncomplicated technological know-how, imaging, prevention, therapy, and more.

Features:
  • Learn from a popular workforce of retina surgeons who deal with all points of administration, together with anatomy, body structure, and pathophysiology; imaging of the macula in ARMD, prevention measures and remedy; and destiny instructions within the field.
  • Gain an exceptional starting place in intravenous fluorescein angiography, indocyanine eco-friendly angiography, and optical coherence tomography, in addition to antiVEGE treatment and comparable new medicinal drugs, optimizing your analysis and therapy options.
  • Understand the numerous switch within the class method of choroidal neovascular membranes in ARMD.
  • Get updated info on treating ARMD secondary to geographic atrophy via phone transplantation and pharmacologic therapies.
  • Easily visualize key points of ARMD because of high quality illustrations and photographs.
  • Find the data you wish quick by way of referencing person chapters that provide complete and inclusive assurance of the subject at hand.
Now with the print variation, benefit from the bundled interactive booklet version, supplying pill, telephone, or on-line entry to:
  • Complete content material with greater navigation 
  • Powerful seek instruments and shrewdpermanent navigation cross-links that pull effects from content material within the publication, your notes, or even the web
  • Cross-linked pages, references, and extra for simple navigation
  • Highlighting software for simpler reference of key content material during the text
  • Ability to take and percentage notes with pals and colleagues
  • Quick reference tabbing to avoid wasting your favourite content material for destiny use

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Extra resources for Age-Related Macular Degeneration

Example text

Unfortunately, most double knockout mice die from a movement disorder at a very young age, thus hindering possibility to study long-term effects. Exogenous Oxidative Conditions: Cigarette Smoke, Hydroquinone, High-Fat Diet, and Blue Light It is unanimously accepted that smoking constitutes the major preventable risk factor for AMD (93–97). Cigarette smoke contains over 4,000 potentially damaging toxins, many of which are pro-oxidants including carbon monoxide, nitric oxide, and hydroquinone (98).

Latest studies have managed to optimize laser parameters to produce advanced lesions more frequently (232). Still, group sizes of 10 monkeys are typically required to document significant effects, and in some studies, smaller group sizes have generated inconclusive results (233,234). Laser Injury in Rabbits and Pigs Rabbit elDirini et al. (235) used rabbits in an attempt to find an intermediate laser-induced CNV model between rodents and primates, thereby avoiding the expense and ethical issues concerning the latter.

Overall, these models contrast with the murine models of wet AMD that are mostly induced mechanically and are explained later in this chapter. LIPID AND GLUCOSE METABOLISM MODELS A growing body of the literature indicates the involvement of lipids, lipoproteins, and glucose in the formation of extracellular lesions in aging BM, basal deposits and drusen, and other AMD hallmarks. Observational studies have indicated that maintaining adequate levels of fatty acids or a low glycemic index (GI) diet may be particularly beneficial for early stages of the disease.

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Age-Related Macular Degeneration by D. Virgil Alfaro III et al.


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